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Innovative Biotechnology

Lactoperoxidase, an enzyme initially discovered in milk, showcases powerful properties. This enzyme plays a crucial role in inhibiting the growth of contaminating bacteria, consequently extending the longevity of milk.

In 1951, researchers discovered the presence of lactoperoxidase in saliva as well. The enzyme inhibits bacterial growth through a specific chemical reaction.

One of the significant actions of lactoperoxidase is the stimulation of hypothiocyanate [OSCN-] production. This compound has the unique ability to infiltrate bacterial cells and impede glycolysis, thereby reducing the energy supply within the cell. This process effectively hinders bacterial growth, showcasing the potent antibacterial capabilities of lactoperoxidase.

Enhancing the Lactoperoxidase System with enzim® Toothpaste

enzim® toothpaste is formulated to enhance your natural saliva defenses by reinforcing the Lactoperoxidase (LPO) system. This is achieved through the synergy of three potent enzymes that play a critical role in the production of OSCN- through the catalysis of the lactoperoxidase system. Two of these enzymes, Amyloglucosidase (AMG) and Glucose Oxidase (GO), work collaboratively to generate additional H2O2. This enhanced enzymatic activity ensures that your oral health is protected and maintained, courtesy of the biotechnological innovations within enzim® toothpaste.

Maintaining Oral Microbiome Balance with enzim® Toothpaste

Normal Situation

Under normal circumstances, a healthy oral cavity ecosystem produces sufficient amounts of H2O2, courtesy of beneficial microbiome in saliva, to keep the lactoperoxidase (LPO) system functioning optimally.

However, various factors can disrupt this balance, reducing the population of good microbiome in the saliva. Such damaging factors include:

  1. Modern diet components, including flavoring, flavor enhancers, colorings, additives, and preservatives.
  2. Use of antiseptic dentifrice products.
  3. Use of Sodium Lauryl Sulphate, which can promote the growth of bad microorganisms in the oral cavity.


enzim® toothpaste comes to the rescue in such situations, providing a means to restore balance in the oral microbiome. Its unique formulation includes enzymes Amyloglucosidase (AMG) and Glucose Oxidase (GO) which generate additional H2O2, a compound essential for the production of extra OSCN-. This replenishment aids in restoring and maintaining a healthy balance in your oral microbiome, supporting overall dental and oral health.

Some extra H2O2 can restore the Balance in the Oral Microflora : enzim® Toothpaste enzymes amyloglucosidase and glucose oxidase deliver some H2O2, necessary for the production of extra OSCN